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New Approach Captures Detailed Mid-Infrared Images for Medical Diagnostics
May 29, 2019 | OSAEstimated reading time: 4 minutes
The researchers demonstrated the imaging speed of their new mid-infrared upconversion spectroscopy approach by tuning the illumination laser to match the peak absorption of a gas flow and acquiring a video with 40 images per second.
They also conducted a pilot study, headed by the team members from Exeter University, in which the system was used to evaluate cancerous and healthy esophageal tissue samples. They found that morphology and spectral classification using their system matched well with the standard stained histopathology images.
“Our upconversion imaging approach is generic and constitutes a major simplification in realizing video-frame-rate, mid-infrared monochromatic imaging,” said Tidemand-Lichtenberg.
“The spectral information provided by this technique could be combined with machine learning to enable faster, and possibly more objective, medical diagnostics based on chemical signatures without the need for staining.”
The research project was funded by the European Commission’s Innovative Training Networks and involved a collaborative team of researchers from The Institute of Photonics Sciences (ICFO) in Spain and DTU Fotonik as well as Exeter University and Gloucestershire Hospitals NHS Foundation Trust, both from the United Kingdom.
About Optica
Optica is an open-access, online-only journal dedicated to the rapid dissemination of high-impact peer-reviewed research across the entire spectrum of optics and photonics. Published monthly by The Optical Society (OSA), Optica provides a forum for pioneering research to be swiftly accessed by the international community, whether that research is theoretical or experimental, fundamental or applied. Optica maintains a distinguished editorial board of more than 50 associate editors from around the world and is overseen by Editor-in-Chief Alex Gaeta, Columbia University, USA.
About The Optical Society
Founded in 1916, The Optical Society (OSA) is the leading professional organization for scientists, engineers, students and business leaders who fuel discoveries, shape real-life applications and accelerate achievements in the science of light. Through world-renowned publications, meetings and membership initiatives, OSA provides quality research, inspired interactions and dedicated resources for its extensive global network of optics and photonics experts.
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