Biologically Powered Chip Created

Estimated reading time: 3 minutes

"We made a macroscale version of this system, at the scale of several millimeters, to see if it worked," Shepard notes. "Our results provide new insight into a generalized circuit model, enabling us to determine the conditions to maximize the efficiency of harnessing chemical energy through the action of these ion pumps. We will now be looking at how to scale the system down."

While other groups have harvested energy from living systems, Shepard and his team are exploring how to do this at the molecular level, isolating just the desired function and interfacing this with electronics. "We don't need the whole cell," he explains. "We just grab the component of the cell that's doing what we want. For this project, we isolated the ATPases because they were the proteins that allowed us to extract energy from ATP."

The ability to build a system that combines the power of solid-state electronics with the capabilities of biological components has great promise. "You need a bomb-sniffing dog now, but if you can take just the part of the dog that is useful -- the molecules that are doing the sensing -- we wouldn't need the whole animal," says Shepard.

"With appropriate scaling, this technology could provide a power source for implanted systems in ATP-rich environments such as inside living cells," added Roseman.

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